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Ask the Where Question; LOCi(R) Is the Answer
JAMA. 2009;302(2):121. Minimally invasive, tubular diskectomy is thought to result in less postoperative pain and more rapid recovery than conventional microdiskectomy in the treatment of sciatica; however, data to support these assumptions are limited.
Context Echocardiographic measures of left ventricular (LV) structure and function are heritable phenotypes of cardiovascular disease. Objective To identify common genetic variants associated with cardiac structure and function by conducting a meta-analysis of genome-wide association data in 5 population-based cohort studies (stage 1) with replication (stage 2) in 2 other community-based ...
Using knowledge of circles, loci and pythagoras to construct parts of a football pitch. I stole this from a tour of a premiership football club who challenged the kids to work out how they make their pitches exactly.
A consortium of European and Australian scientists doing a genome-wide association study found three gene variants were strongly linked to melanoma risk: two of them had previously been linked to pigmentation, freckling and sun sensitivity, and one was a new discovery.
July 6, 2009 – Studies of massive numbers of people in Europe and Australia has found that people with the greatest number of moles are the people most likely to develop the most dangerous form of skin cancer, melanoma, which is on the increase.
Tracking the dance of DNA and structural proteins within the nucleus shows that placement makes the difference between gene activity and silence
( University of Leeds ) Research shows the genetic connection between moles and melanoma -- and why the more moles a person has, the more susceptible they are to the disease
Cohesin-mediated sister chromatid cohesion is essential for chromosome segregation and post-replicative DNA repair. In addition, evidence from model organisms and from human genetics suggests that cohesin is involved in the control of gene expression. This non-canonical role has recently been rationalized by the findings that mammalian cohesin complexes are recruited to a subset of DNase I ...
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