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ORIGINAL ARTICLE: Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome

Published August 27, 2008, 2:30 pm, New England Journal of Medicine

This study examined genotype and body-mass index in patients with the Wilms' tumor, aniridia, genitourinary anomalies, and mental retardation (WAGR) syndrome. The related genes WT1 and PAX6 are on chromosome 11p13, centromeric to brain-derived neurotrophic factor (BDNF), an important gene in energy homeostasis. BDNF haploinsufficiency was linked to childhood-onset obesity and reduced levels of ...

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Software faciliates cardiovascular diagnosis.

Published August 26, 2008, 5:54 am, ThomasNet

Web-based ProSolvĀ® CardioVascular v4.0 provides full viewing and reporting capabilities using Web communication protocols, secured via SSL. Program includes pediatric echo report and Z-score module, allowing users to report more than 40 pediatric measurements and calculations against normal ranges and Z-scores. For nuclear cardiology, Invia 4DM-spect v5.2 is supported. Other features include ...

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