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Study Identifies How Tamoxifen Stimulates Uterine Cell Growth And Cancer

Published July 4, 2009, 4:07 am, Medical News Today

UCSF researchers have identified a new "feed-forward" pathway linking estrogen receptors in the membrane of the uterus to a process that increases local estrogen levels and promotes cell growth.

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Research Identifies How Tamoxifen Stimulates Uterine Cell Growth And Cancer

Published July 3, 2009, 9:59 am, redOrbit

UCSF researchers have identified a new "feed-forward" pathway linking estrogen receptors in the membrane of the uterus to a process that increases local estrogen levels and promotes cell growth.The research is significant in helping determine why tamoxifen and other synthetic estrogens are linked to increased rates of endometriosis and uterine cancer, and identifies a pathway that could be ...

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Important Therapeutic Target For Breast Cancer: Newly Appreciated Membrane Estrogen Receptor

Published July 3, 2009, 3:08 am, Medical News Today

New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in the July edition of the journal Molecular Endocrinology.

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Mathematical Model Predicts Factors Driving Tumor Invasion

Published July 2, 2009, 4:03 pm, PhysOrg

Tumors are complex collections of cells whose behavior has proven difficult to understand, let alone predict. As a result, oncologists are often surprised by how a particular patient responds to a given course of therapy.

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Plants' internal clock can improve climate-change models

Published July 2, 2009, 3:48 pm, PhysOrg

The ability of plants to tell the time, a mechanism common to all living beings, enables them to survive, grow and reproduce. In a study published in the latest issue of the prestigious journal Ecology Letters, an international team has studied this circadian clock from a molecular viewpoint and has found an ecological implication: it makes climate change scenarios and CO2 level figures more ...

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Digital Entertainer brings PC content to big screen

Published July 2, 2009, 3:03 pm, PhysOrg

So there you are with all those videos, photos and MP3 music files, and the only place you can play all that digital entertainment is on your computer. It's probably sequestered away somewhere in the room you've designated to be your home office.

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Study identifies how tamoxifen stimulates uterine cell growth and cancer

Published July 2, 2009, 1:46 pm, EurekAlert!

( University of California - San Francisco ) University of California - San Francisco researchers have identified a new "feed-forward" pathway linking estrogen receptors in the membrane of the uterus to a process that increases local estrogen levels and promotes cell growth.

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Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer

Published July 1, 2009, 12:03 pm, PhysOrg

New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in the July edition of the journal Molecular Endocrinology. This new study by Edward Filardo, MD, and his research team further supports earlier published work by the group that ...

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Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer

Published July 1, 2009, 7:47 am, EurekAlert!

( Lifespan ) New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer.

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New Take On Growth Factor Signaling In Tamoxifen Resistance

Published June 30, 2009, 7:37 am, Science Daily

Differences in growth factor (GF) signaling may cause the poor prognosis in some breast cancer cases. A new study suggests that some estrogen receptor-positive breast cancers respond poorly to tamoxifen because of increased GF signaling.

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