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Molecular Machinery Related To Stem Cell Fate Revealed By Xie Lab
Published June 29, 2009, 3:10 am, Medical News Today
The Stowers Institute's Xie Lab has revealed how the BAM protein affects germline stem cell differentiation and how it is involved in regulating the quality of stem cells through intercellular competition. The work was published by PNAS Early Edition. Maintaining the proper balance between stem cell self-renewal and differentiation is critical for normal homeostasis.
MicroRNA-mediated switching of chromatin-remodelling complexes in neural development
Published June 28, 2009, 9:57 am, Nature
One of the most distinctive steps in the development of the vertebrate nervous system occurs at mitotic exit when cells lose multipotency and begin to develop stable connections that will persist for a lifetime. This transition is accompanied by a switch in ATP-dependent chromatin-remodelling mechanisms that appears to coincide with the final mitotic division of neurons. This switch involves the ...
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