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PharmaEngine wins approval for Phase II pancreatic cancer study

Published December 5, 2008, 2:49 am, Pharmaceutical Business Review

PharmaEngine, a biopharmaceutical company, has received approval of an investigational new drug application from the FDA for PEP02, a liposome formulation of irinotecan in a Phase II study in patients with metastatic pancreatic cancer.

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TorreyPines' NGX426 meets endpoints in reducing spontaneous pain

Published December 5, 2008, 1:51 am, PharmaBiz

TorreyPines Therapeutics, Inc announced that oral administration of NGX426, an AMPA/kainate-type glutamate receptor antagonist, demonstrated a statistically significant reduction in spontaneous pain, hyperalgesia (abnormally increased pain state) and allodynia (pain resulting from normally non-painful stimuli to the skin) compared to placebo following intradermal injections of capsaicin in a ...

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ConjuChem's PC-DAC(TM):Exendin-4 Lowers Glucose And Weight In Phase II Diabetes Trials

Published December 4, 2008, 7:13 am, Medical News Today

ConjuChem Biotechnologies, Inc. (TSX:CJB) announced preliminary results today showing that its Type 2 diabetes product, PC-DAC(TM):Exendin-4, achieved statistically significant reductions in HbA1c and weight in its two Phase II clinical trials.

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Alkermes Initiates Clinical Trial for ALKS 33, a Novel Oral Molecule with Potential Benefits in Addiction and Other ...

Published December 4, 2008, 5:47 am, Centre Daily Times

Alkermes, Inc. (NASDAQ: ALKS) today announced the initiation of a phase 1 study of ALKS 33, an oral opioid modulator for the potential treatment of addiction and other central nervous system (CNS) disorders. ALKS 33 is the company’s first novel, small molecule drug candidate to enter the clinic. The molecule builds on Alkermes’ scientific expertise in brain reward pathways as well as the ...

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Alkermes Initiates Clinical Trial for ALKS 33, a Novel Oral Molecule with Potential Benefits in Addiction and Other ...

Published December 4, 2008, 5:30 am, Business Wire via Yahoo! Finance

CAMBRIDGE, Mass.----Alkermes, Inc. today announced the initiation of a phase 1 study of ALKS 33, an oral opioid modulator for the potential treatment of addiction and other central nervous system disorders.

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Data on Stapled Peptide Drugs to Be Presented at ASH Annual Meeting

Published December 4, 2008, 5:00 am, Business Wire via Yahoo! Finance

CAMBRIDGE, Mass.----Aileron Therapeutics announced today that investigators from Aileron and the Dana-Farber Cancer Institute will present data from multiple preclinical studies on stapled peptide drug candidates at the 50th Annual Meeting of the American Society of Hematology in San Francisco, Calif., December 6 to 9, 2008.

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ConjuChem's PC-DAC(TM):Exendin-4 Lowers Glucose and Weight in Phase II Diabetes Trials

Published December 3, 2008, 2:52 pm, PR Newswire via Yahoo! Finance

ConjuChem Biotechnologies, Inc. announced preliminary results

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ConjuChem's PC-DAC(TM):Exendin-4 Lowers Glucose and Weight in Phase II Diabetes Trials

Published December 3, 2008, 1:23 pm, PR Newswire via Yahoo! Finance

Product Extremely Well Tolerated -

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PharmaEngine Receives Approval Of US IND Application For A Phase II Study Of PEP02 (Liposome Irinotecan Injection) In ...

Published December 3, 2008, 12:11 pm, Medical News Today

PharmaEngine, Inc. announced today that it has received approval of an Investigational New Drug (IND) application from the U.S. FDA for PEP02, a liposome formulation of irinotecan in a phase II study in patients with metastatic pancreatic cancer.

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Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S., Named New Director of the National Institute of Environmental Health ...

Published December 3, 2008, 9:55 am, National Institutes of Health

Dr. Raynard S. Kington, acting director of the National Institutes of Health (NIH), today announced the appointment of Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S., as director of the National Institute of Environmental Health Sciences (NIEHS). Dr. Birnbaum, who is currently a senior advisor at the Environmental Protection Agency (EPA), where she served for 16 years as director of the Experimental ...

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