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Treatment Of Rare Type Of Bone Tumour: Promising Results With Denosumab

Published February 10, 2010, 3:45 am, Medical News Today

Denosumab is a targeted therapy to prevent bone loss. It stops progressive bone destruction and tumour spread in some patients with inoperable giant-cell tumour (GCT) of bone. An article published Online First in The Lancet Oncology reports this could change standard treatment practice. Breaking new ground, this work is the first to clearly show a promising systemic treatment option for this ...

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Activist Investor Pushes Celera to Divest Merck Bone Drug Royalties

Published February 9, 2010, 6:05 pm, BioWorld

The Biotechnology Value Fund (BVF), a historically activist investor group, revealed in a 13-D filing Tuesday the reason for its recent interest in diagnostics firm Celera Corp.: BVF wants Celera to spin out its royalty interest in Merck & Co. Inc.'s Phase III osteoporosis drug, odanacatib.

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Denosumab Demonstrated Superiority Over Zometa(R) In Pivotal Phase 3 Head-to-Head Trial In Prostate Cancer Patients ...

Published February 9, 2010, 4:19 am, Medical News Today

Amgen (Nasdaq: AMGN) announced that a pivotal, Phase 3, head-to-head trial evaluating denosumab versus Zometa® (zoledronic acid) in the treatment of bone metastases in 1,901 men with advanced prostate cancer met its primary and secondary endpoints. Denosumab demonstrated superiority over Zometa for both delaying the time to the first on-study skeletal related event (SRE) (fracture, radiation to ...

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Denosumab Demonstrated Superiority Over Zometa(R) in Pivotal Phase 3 Head-to-Head Trial in Prostate Cancer Patients ...

Published February 8, 2010, 7:08 pm, redOrbit

THOUSAND OAKS, Calif., Feb.

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Denosumab Demonstrated Superiority Over Zometa(R) in Pivotal Phase 3 Head-to-Head Trial in Prostate Cancer Patients ...

Published February 8, 2010, 3:20 pm, PR Newswire via Yahoo! Finance

Amgen today announced that a pivotal, Phase 3, head-to-head trial evaluating denosumab versus Zometa® in the treatment of bone metastases in 1,901 men with advanced prostate cancer met its primary and secondary endpoints.

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