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Dictyostelium cells shown to lay 'breadcrumb trail' as first step in multicellular formation

Published December 1, 2008, 8:28 am, PhysOrg

When starved of their food source and then presented with a chemoattractant signal like cAMP, individual Dictyostelium cells acquire a polarized morphology and aggregate to form a migrating stream. This is the first step in a developmental program that culminates in the formation of a multicellular organism. Kriebel et al. show how this streaming response is coordinated at a single-cell level in ...

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Breaking BubR1 Mimics Genetic Shuffle Seen In Cancer Cells

Published November 26, 2008, 10:26 pm, Science Daily

A study of how BubR1 helps make sure chromosomes are equally distributed during mitosis might explain how the process of cell division goes so awry in cancer, according to researchers. Mutations in BubR1 lead to a genetic rearrangement similar to a process that allows cancer cells to evade destruction by medical treatment. Inhibiting BubR1 could be a strategy that enhances the killing power of ...

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MIT Engineers Show How Tiny Cell Proteins Generate Force To 'Walk'

Published November 26, 2008, 2:53 am, BioresearchOnline

MIT researchers have shown how a cell motor protein exerts the force to move, enabling functions such as cell division. Kinesin, a motor protein that also carries neurotransmitters, "walks" along cellular beams known as microtubules.

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MIT Engineers Show How Tiny Cell Proteins Generate Force To 'Walk'

Published November 25, 2008, 4:11 am, Medical News Today

MIT researchers have shown how a cell motor protein exerts the force to move, enabling functions such as cell division. Kinesin, a motor protein that also carries neurotransmitters, "walks" along cellular beams known as microtubules. For the first time, the MIT team has shown at a molecular level how kinesin generates the force needed to step along the microtubules.

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Researchers show how a cell motor protein exerts the force to move

Published November 24, 2008, 11:05 pm, News-Medical-Net

Kinesin, a motor protein that also carries neurotransmitters, "walks" along cellular beams known as microtubules. For the first time, the MIT team has shown at a molecular level how kinesin generates the force needed to step along the microtubules.

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AnaSpec Releases 4 New Phosphospecific Anti-Tau Antibodies

Published November 24, 2008, 7:06 pm, PR.com

AnaSpec is excited to announce the release of 4 more new phosphospecific anti-Tau antibodies. This represents the industry’s largest collection of anti-Tau antibodies - 17 phosphospecific and 9 non-phosphospecific antibodies. AnaSpec’s expertise in phosphopeptide synthesis combined with excellent affinity purification has resulted in the production of an anti-Tau to phosphoserine at position 235 ...

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