Low-density Lipoprotein (Ldl) Cholesterol

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Amarin Receives Special Protocol Assessment Agreement from the FDA for Phase 3 Trial in Mixed Dyslipidemia

Published July 9, 2009, 5:42 am, Business Wire via Yahoo! Finance

DUBLIN----Amarin Corporation plc today announced that it has reached agreement with the U.S. Food and Drug Administration under a Special Protocol Assessment for its planned Phase 3 clinical trial of AMR101 in patients with mixed dyslipidemia.

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Yale Researchers Identify Gene's Role In Promoting Atherosclerosis

Published July 9, 2009, 4:15 am, Medical News Today

Yale University researchers have found that a single gene plays a key role in the development of atherosclerosis in mice. The research provides insight into the causes of atherosclerosis, or the hardening of the arteries caused by a buildup of plaque. The research appears in the July 8th issue of the journal Cell Metabolism.

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Genes Linked to Cholesterol in Cells Are Identified

Published July 8, 2009, 12:28 pm, MedicineNet.com

Title: Genes Linked to Cholesterol in Cells Are Identified Category: Health News Created: 7/8/2009 7:00:00 AM Last Editorial Review: 7/8/2009

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Genes Linked to Cholesterol in Cells Are Identified

Published July 7, 2009, 10:01 am, Health Scout

Discovery could lead to new treatment targets, researchers say.

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Yale Researchers Identify Gene’s Role in Promoting Atherosclerosis

Published July 7, 2009, 9:34 am, Yale University Office of Public Affairs

Yale University researchers have found that a single gene plays a key role in the development of atherosclerosis in mice. The research provides insight into the causes of atherosclerosis, or the hardening of the arteries caused by a buildup of plaque.

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Genes Linked to Cholesterol in Cells Are Identified

Published July 7, 2009, 9:03 am, HealthDay via Yahoo! News

TUESDAY, July 7 (HealthDay News) -- Twenty genes that play major roles in controlling cholesterol within cells have been identified by German researchers, who said that some of the genes may play a role in heart disease risk and offer new targets for drug treatment.

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Tekmira Begins Phase I Trial of siRNA Drug for Hypercholesterolemia

Published July 6, 2009, 9:32 am, GenomeWeb News

Tekmira Pharmaceuticals announced last week that it has begun a phase I study of its siRNA-based treatment for hypercholesterolemia.

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Tekmira Pharmaceuticals Initiates ApoB SNALP Phase 1 Clinical Trial

Published July 5, 2009, 3:08 am, Medical News Today

Tekmira Pharmaceuticals Corporation (TSX:TKM) announced that it has initiated a Phase 1 human clinical trial for ApoB SNALP. ApoB SNALP, Tekmira's lead RNAi therapeutic product candidate, is being developed as a treatment for patients with elevated low-density lipoprotein (LDL) cholesterol, or "bad" cholesterol, who are not well served by current therapy.

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Tekmira Pharmaceuticals Initiates ApoB SNALP Phase 1 Clinical Trial

Published July 2, 2009, 11:18 pm, PharmaceuticalOnline

Tekmira Pharmaceuticals Corporation (TSX:TKM) announced today that it has initiated a Phase 1 human clinical trial for ApoB SNALP.ApoB SNALP, Tekmira's lead RNAi therapeutic product candidate, is being developed as a treatment for patients with elevated low-density lipoprotein (LDL) cholesterol, or "bad" cholesterol, who are not well served by current therapy.

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