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Curbing hormones' effects in obese patients could aid against breast cancer
Published December 1, 2008, 2:27 pm, EurekAlert!
( Emory University ) Results from cell culture studies suggest a class of anticancer compounds called EGFR inhibitors, largely written off for breast cancers, could be effective in obese patients. The hormones leptin and IGF-1 synergistically stimulate migration and invasion in breast cancer cells. EGFR inhibitors block this stimulation.
cell culture culture studies egfr emory university
hormones igf 1 invasion migration
obese patients
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Curbing hormones' effects in obese patients could aid against breast ... - Genetic Engineering News
Once-promising drugs that were abandoned in the fight against breast cancer still could be effective in obese patients, new research suggests. In laboratory tests, hormones produced by fat cells stimulate breast cancer cells to migrate and invade ...
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