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Published October 13, 2008, 8:55 am, PharmiWeb

The new oral antidiabetic drugs sitagliptin and vildagliptin work by boosting the guts incretin hormones GLP-1 and GIP to regulate insulin secretion following food intake and glucagon secretion when blood sugar is low.

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FDA continues review of Takeda's NDA for Alogliptin

Published October 12, 2008, 3:31 pm, News-Medical-Net

Takeda Pharmaceutical Company Limited has announced that Takeda Global Research and Development Center, Inc., a wholly owned United States (U.S.) subsidiary, received notification that the U.S. Food and Drug Administration (FDA) will not be able to complete its review of the alogliptin New Drug Application (NDA) by the Prescription Drug User Fee Act (PDUFA) date of October 27, 2008.

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Small Intestine Can Sense And React To Bitter Toxins In Food

Published October 11, 2008, 3:06 pm, Medical News Today

Toxins in food often have a bad, bitter taste that makes people want to spit them out. New UC Irvine research finds that bitterness also slows the digestive process, keeping bad food in the stomach longer and increasing the chances that it will be expelled.

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FDA Continues Review Of Takeda's New Drug Application For Alogliptin (SYR-322), A DPP-4 Agent For Type 2 Diabetes

Published October 11, 2008, 3:07 am, Medical News Today

Takeda Pharmaceutical Company Limited ("Takeda") announced that Takeda Global Research and Development Center, Inc., a wholly owned United States (U.S.) subsidiary, received notification that the U.S.

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Small Intestine Senses Bitter Toxins in Food

Published October 10, 2008, 12:29 pm, MedicineNet.com

Title: Small Intestine Senses Bitter Toxins in Food Category: Health News Created: 10/10/2008 2:00:00 AM Last Editorial Review: 10/10/2008

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JCI Online Early Table Of Contents: Oct. 9, 2008

Published October 10, 2008, 8:07 am, Medical News Today

VASCULAR BIOLOGY: A real-time view of blood flow through the pancreas A team of researchers at Vanderbilt University, Nashville, has developed a new microscopy approach that enabled them to image, in real time, the flow of blood in mouse pancreatic islets of Langerhans. The pancreatic islets of Langerhans have a central role in regulating the amount of glucose in the blood.

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FDA Continues Review Of Takeda's New Drug Application For Alogliptin (SYR-322), A DPP-4 Agent For Type 2 Diabetes

Published October 10, 2008, 6:07 am, Medical News Today

Takeda Pharmaceutical Company Limited ("Takeda") today announced that Takeda Global Research and Development Center, Inc., a wholly owned United States (U.S.) subsidiary, received notification that the U.S.

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Small Intestine Can Sense And React To Bitter Toxins In Food

Published October 9, 2008, 4:23 pm, Science Daily

Toxins in food often have a bad, bitter taste that makes people want to spit them out. New research finds that bitterness also slows the digestive process, keeping bad food in the stomach longer and increasing the chances that it will be expelled.

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JCI online early table of contents: Oct. 9, 2008

Published October 9, 2008, 2:29 pm, EurekAlert!

( Journal of Clinical Investigation ) This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, Oct. 9, 2008, in the JCI: A low-cholesterol diet leaves a bitter taste in the gut; A real-time view of blood flow through the pancreas; The protein NFATc1: a master controller of bone destruction; Slow, slow, quick, quick, slow: ...

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Small Intestine Senses Bitter Toxins in Food

Published October 9, 2008, 2:02 pm, HealthDay via Yahoo! News

THURSDAY, Oct. 9 (HealthDay News) -- If bitter-tasting food makes you feel ill, it may just be your digestive system doing its job, a new report says.

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