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Chronic pancreatitis (CP) is a chronic clinical disorder characterized by irreversible damage to the pancreas, the development of histologic evidence of inflammation and fibrosis, and eventually the destruction and permanent loss of exocrine and endocrine tissue. Imaging or function tests may not reveal early CP, and the results of these tests do not necessarily correlate with each other.
A research group from Japan investigated whether serum chemokine and cytokine levels can become useful biological and functional markers to assess the severity of chronic pancreatitis (CP). They found that the measurement of serum F-fractalkine is useful to diagnose earlystage CP. Moreover, the combined determination of both, s-fractalkine and TGF-beta1, in human sera may be helpful in ...
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