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IP Roundup

Published February 9, 2010, 9:45 am, GenomeWeb News

The University of Arkansas of Little Rock has received US Patent No. 7,659,062, "Gene expression profiling of uterine serous papillary carcinomas and ovarian serous papillary tumors."

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Journal Of Clinical Investigation Online News Feb. 8, 2010

Published February 9, 2010, 7:18 am, Medical News Today

NEPHROLOGY: New approach to treating the kidney disease Alport syndrome? Alport syndrome is a progressive hereditary kidney disease with no definitive therapy. It is caused by mutations in any of the collagen IV genes (COL4A3, COL4A4, and COL4A5). Motoko Yanagita and colleagues, at Kyoto University Graduate School of Medicine, Japan, have now identified a role for the protein USAG-1 in the ...

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Rab25: a suppressor of tumor formation in intestines?

Published February 8, 2010, 8:30 pm, Science Daily

Colorectal adenocarcinoma accounts for the majority of cases of colorectal cancer. A series of genetic mutations in the cells lining the colon (intestinal epithelial cells) is thought to be the cause of colorectal adenocarcinoma. By studying mouse models of colon cancer and tissue from individuals with colorectal adenocarcinoma, researchers have now identified RAB25 as one gene that might be ...

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JCI online early table of contents: Feb. 8, 2010

Published February 8, 2010, 2:28 pm, EurekAlert!

( Journal of Clinical Investigation ) This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Feb. 8, 2010, in the JCI: Marker of Ewing sarcoma: potential new drug target?; Enhancing arrest of cell growth to treat cancer in mice; New approach to treating the kidney disease Alport syndrome?; Role for the protein HIF-2 ...

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Transplantation of pulmonary progenitor cells derived from hESCs promising for acute lung injury

Published February 3, 2010, 11:06 pm, News-Medical-Net

Stem cell researchers exploring a new approach for the care of respiratory diseases report that an experimental treatment involving transplantable lung cells was associated with improved outcomes in tests on mice with acute lung injury. The lung cells were derived from human embryonic stem cells (hESCs). Findings by investigators at The University of Texas Health Science Center at Houston are ...

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Experimental Stem Cell Treatment Arrests Acute Lung Injury In Mice

Published February 3, 2010, 2:08 pm, redOrbit

Stem cell researchers exploring a new approach for the care of respiratory diseases report that an experimental treatment involving transplantable lung cells was associated with improved outcomes in tests on mice with acute lung injury.

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Experimental stem cell treatment arrests acute lung injury in mice, study shows

Published February 3, 2010, 7:24 am, Science Daily

Stem cell researchers exploring a new approach for the care of respiratory diseases report that an experimental treatment involving transplantable lung cells was associated with improved outcomes in tests on mice with acute lung injury. The lung cells were derived from human embryonic stem cells.

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Loss Of Gene Function Makes Prostate Cancer Cells More Aggressive

Published February 3, 2010, 6:32 am, Medical News Today

Prostate cancer cells are more likely to spread to other parts of the body if a specific gene quits functioning normally, according to new data from researchers at UT Southwestern Medical Center. Certain prostate cancer cells can be held in check by the DAB2IP gene. The gene's product, the DABIP protein, acts as scaffolding that prevents many other proteins involved in the progression of ...

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Prostate cancer cells more likely to spread with specific gene function loss

Published February 3, 2010, 12:52 am, New Kerala

Washington, Feb 3 : A new research has shown that prostate cancer cells are more likely to spread to other parts of the body if a specific gene quits functioning normally.

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Study could provide potential therapeutic strategies for treating prostate cancer

Published February 2, 2010, 9:52 pm, News-Medical-Net

Prostate cancer cells are more likely to spread to other parts of the body if a specific gene quits functioning normally, according to new data from researchers at UT Southwestern Medical Center.

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