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Gene Mutation May Cause Immature Lungs In Newborns
Published December 2, 2008, 8:28 pm, Science Daily
Scientists have identified a gene critical to lung maturation in newborns and the production of surfactant, which lines lung tissues and prevents the lungs from collapsing. Scientists deleted the Foxm1 gene in embryonic mice. Lungs in the mice did not fully mature and the mice died shortly after birth from respiratory distress.
Curbing Hormones' Effects In Obese Patients Could Aid Against Breast Cancer
Published December 2, 2008, 9:11 am, Medical News Today
Once-promising drugs that were abandoned in the fight against breast cancer still could be effective in obese patients, new research suggests. In laboratory tests, hormones produced by fat cells stimulate breast cancer cells to migrate and invade surrounding tissues, scientists at Emory University School of Medicine found.
02.12.2008 - DJ HUGIN NEWS/Micromet Expands Committed Equity Financing Facility to $75 Million
Published December 2, 2008, 5:23 am, 4investors
Corporate news announcement processed and transmitted by Hugin AS. The issuer is solely responsible for the content of this announcement. =--------------------------------------------------------------------- =-------------
Micromet Expands Committed Equity Financing Facility to $75 Million
Published December 2, 2008, 4:00 am, PR Newswire via Yahoo! Finance
Micromet, Inc. , a biopharmaceutical company developing novel, proprietary antibodies for the treatment of cancer, inflammation and autoimmune diseases, today announced that it has entered into an agreement expanding its Committed Equity Financing Facility with Kingsbridge Capital Limited, a private investment group.
EGFR inhibitors show promise for obesity
Published December 2, 2008, 2:50 am, News-Medical-Net
Once-promising drugs that were abandoned in the fight against breast cancer still could be effective in obese patients, new research suggests.
JCI online early table of contents: Dec. 1, 2008
Published December 1, 2008, 2:28 pm, EurekAlert!
( Journal of Clinical Investigation ) This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, Dec. 1, 2008, in the JCI, including "Harnessing miRNA natural gene repressors for anticancer therapy," "The protein IRBIT helps epithelial cells secrete fluid" and "Lactoferrin explains why apoptotic cell death isn't inflammatory."
Curbing hormones' effects in obese patients could aid against breast cancer
Published December 1, 2008, 2:27 pm, EurekAlert!
( Emory University ) Results from cell culture studies suggest a class of anticancer compounds called EGFR inhibitors, largely written off for breast cancers, could be effective in obese patients. The hormones leptin and IGF-1 synergistically stimulate migration and invasion in breast cancer cells. EGFR inhibitors block this stimulation.
Does ascorbic acid promote neuroprotection in diabetic rats?
Published December 1, 2008, 6:44 am, EurekAlert!
A research group from the State University of Maringa in Brazil investigated the effect of ascorbic acid dietary supplementation on myenteric neurons and epithelial cell proliferation of the jejunum of adult rats with chronic diabetes mellitus. They found that there was no observation of alteration of the cellular proliferation of the jejunum mucosa layer of rats with chronic diabetes mellitus ...
Stem-cell science moves forward
Published November 30, 2008, 12:25 pm, Minneapolis-St. Paul Star Tribune
A bronchial transplant was remarkable not in itself, but because of its stem-cell bioengineering.
Method By Which A Protein That Determines Cell Polarity Prevents Breast Cancer
Published November 30, 2008, 3:13 am, Medical News Today
In breast tissue, cells lining the breast's ducts have a certain shape that is required to maintain both organ structure and function. All breast cancers display a loss of this characteristic organization, but very little is known about the molecules and pathways that regulate tissue structure and the role they play during cancer.
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