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Researchers Map All Fragile Sites Of Yeast Saccharomyces Cerevisiae's Genome

Published February 9, 2010, 3:18 pm, redOrbit

Dr. François Robert and colleagues have accomplished a technical breakthroughThe research group of Dr. François Robert, a researcher at the Institut de recherches cliniques de Montréal (IRCM), in collaboration with the team of Dr.

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Researchers map all the fragile sites of the yeast Saccharomyces cerevisiae's genome

Published February 9, 2010, 12:01 pm, EurekAlert!

( Institut de recherches cliniques de Montreal ) Dr. François Robert, a researcher at the Institut de recherches cliniques de Montréal, in collaboration with the team of Dr. Daniel Durocher (Samuel Lunenfeld Research Institute and University of Toronto) accomplished a technical breakthrough: they mapped all the fragile sites of a living organism, the budding yeast Saccharomyces cerevisiae. The ...

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New Sequencing Technique Helps Identify Regulatory Region Involved in Diabetes

Published February 9, 2010, 10:45 am, GenomeWeb News

Researchers from the University of North Carolina have developed a sequencing technique to create maps of regulatory regions in the genome, and used it to identify a gene variant involved in diabetes.

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Idelle Davidson: Memories Never Go Away, New Study Suggests

Published February 8, 2010, 12:51 pm, The Huffington Post

Li-Huei Tsai, Ph.D. concluded, "This recovery of long-term memory was really the most remarkable finding. Memories are not really erased in disorders as Alzheimer's, but are rendered inaccessible."

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Mitosis [Neurotopia]

Published February 7, 2010, 9:47 pm, ScienceBlogs

Since Sci wrote so recently about the preservation of somatic cells and gametes for species regulation, she thought it might be a good idea to run through some basic concepts. REALLY basic. Like the stuff you had in high school and forgot. That kind of basic. She was also inspired in this post by reading so recently about HeLa cells, and how they allowed scientists to make great strides in the ...

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Tbx3 improves the germ-line competency of induced pluripotent stem cells

Published February 7, 2010, 10:11 am, Nature

Induced pluripotent stem (iPS) cells can be obtained by the introduction of defined factors into somatic cells. The combination of Oct4 (also known as Pou5f1), Sox2 and Klf4 (which we term OSK) constitutes the minimal requirement for generating iPS cells from mouse embryonic fibroblasts. These cells are thought to resemble embryonic stem cells (ESCs) on the basis of global gene expression ...

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This Week in Science

Published February 5, 2010, 8:45 am, GenomeWeb News

In Science this week, a Japanese research team reports that multiple copies of genes coding for ribosomal RNA helps protect the yeast genome following DNA damage.

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Scientists map out regulatory regions of genome, hot spots for diabetes genes

Published February 4, 2010, 9:17 pm, Science Daily

Researchers have generated a complete map of the areas of the genome that control which genes are "turned on" or "off." The discovery, made in pancreatic islet cells, opens new avenues for understanding the genetic basis of type 2 diabetes and other common illnesses.

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International Team Maps Methylation Changes During Cellular Differentiation

Published February 4, 2010, 7:30 am, GenomeWeb News

NEW YORK (GenomeWeb News) – A team of researchers from Singapore and the US has mapped and compared DNA methylation changes across the genome in human cells at three progressive stages of differentiation.

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Link Between Human Birth Defect Syndrome And Cancer Metastasis Explored By Stanford Researchers

Published February 4, 2010, 7:18 am, Medical News Today

Some cells are natural rule-breakers. Neural crest cells for example, not only migrate throughout the body during development (most cells are more selective in their wandering), they are also more developmentally flexible than their predecessors (a no-no for nearly all cell types). Now researchers at the Stanford University School of Medicine have shown that a protein that controls DNA ...

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