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UroToday.com - The current gold standard for diagnosis of prostate cancer is the Transrectal Ultrasound (TRUS) guided prostate biopsy, initiated by elevated PSA-levels or a Digital Rectal Examination (DRE) suspicious for prostate cancer. However TRUS and TRUS-guided biopsies are known to have high false-negative rates, up to 30% with random sextant biopsies 1, 2.
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