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Calcium flickers steer cell migration

Published January 5, 2009, 5:53 am, Nature

Directional movement is a property common to all cell types during development and is critical to tissue remodelling and regeneration after damage. In migrating cells, calcium has a multifunctional role in directional sensing, cytoskeleton redistribution, traction force generation, and relocation of focal adhesions. Here we visualize high-calcium microdomains (|[lsquo]|calcium flickers|[rsquo]|) ...

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